Comparatively, probiotic use is much safer than antibiotic use.
Instead of eliminating both helpful and harmful bacteria like antibiotics, probiotics introduced in the right quantities can turn the tables, restraining the development of harmful bacterias while boosting good bacteria.
Probiotics like Bacillus clausii, Bacillus subtilis, Bacillus coagulans, Bifidobacteria, Lactobacillus, etc. are recognized and continuously studied for their safety and remarkable effectiveness.
Currently, there are some technical barriers when producing microbial products containing probiotics. These barriers and challenges affect the ultimate effectiveness, sustainability, and durability of finished products:
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Probiotics that are alive, activated, or exhibit metabolic activities, tend to not survive the storage and transportation stages of the finished product.
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This is why traditionally, "live probiotics" products cannot be stored for long and become ineffective as soon as they leave the factory for transportation.
In the sector of probiotic supplements for gut health, most products contain probiotic strains like Lactobacillus and Bifidobacteria which cannot form "spore" status and are not able to survive through transportation, storage, extreme temperatures or stomach acid. Rendering them hugely ineffective and mostly "dead" even before reaching the intestinal microflora.
Lactobacillus
Bifidobacteria
Spore probiotics
Only in the "spore" status where bacteria are enclosed and protected by a durable shell cover can probiotics overcome the technical barriers listed above.
Live spore probiotics have time durability, transportation, and storage durability, as well as heat and acid resilience.
TURNING PROBIOTICS INTO SPORE FORM IS NOT DIFFICULT, THE CHALLENGE LIES IN MAINTAINING SUSTAINABILITY OF PROBIOTICS' SPORE STATUS THROUGH FLUCTUATIONS OF THE EXTERNAL ENVIRONMENT
The Live Spore Probiotics SPL Technology innovation of Dr. Nguyen Hoa Anh and his colleagues at the National Key Library of Enzyme and Protein Technology holds great scientific significance for microbial biotechnology. The SPL innovation and methodology has been proven and recognized for its capacity to not only resolve traditional technical barriers of live probiotics production but also opening new doors for the future of microbial biotechnology and humankind.
Technology breakthroughs
The Dangers of Antibiotic Use and Antibiotic-Resistance
Antibiotics support the body by stopping infections and attacks caused by harmful bacterias. Unfortunately, antibiotics also end up killing helpful bacteria like probiotics, causing imbalance in the microbiome, releasing toxins that affect the health of many other organs, and side-effects like inflammation, allergies, and digestive disorders. Side-effects of antibiotics could lead to the development of more serious diseases but more importantly, pose risks of generating widespread super-bacteria that are drug-resistant, vaccine-resistant, and antibiotic-resistant.
Probiotics: The Solution & The Future
HEAT RESISTANT
AND TIME DURABILITY
Helpful bacteria like Bacillus clausii, Bacillus subtilis, and Bacillus coagulans can maintain long term spore status, having limitless durability to sustain lengthy transportation and storage even at extremely cold or high temperatures up to 60-70*C.
ACID DURABILITY
Nearly all probiotic spores will be acid-resistant and able to bypass even stomach acid to reach the intestinal microflora and fully germinate.
THE BEST TRANSMITTED
DOSAGE FORM
For optimum effectiveness, probiotics should come in mixtura form. In reality, this is difficult and poses high risks of spores re-germinating into bacteria form during storage or transportation. Dr. Anh's SPL innovation overcomes this limitation as well, ensuring probiotics stay in spore form and do not germinate until they reach their destination.
*Though the first probiotics spore mixtura was invented in 1959, there have been few big pharmaceutical firms in the world capable of successfully producing sustainable probiotics spore mixtura on a larger and consistent scale.
Multi-Stage Quality Control Policies
1. Quality Control of Raw Materials
2. Quality Control of Production Processes
3. Quality Control of Finished Product
